Epitalon

Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology. It is one of the most extensively studied peptides in longevity, telomere biology, and neuroendocrine regulation research, with over 40 years of preclinical and clinical research behind it.

Telomere Biology Research
Epitalon is most widely studied for its role in telomerase activation — the enzyme responsible for maintaining and elongating telomere length. Research has explored its ability to stimulate telomerase expression in somatic cells, making it one of the most cited compounds in cellular ageing and longevity research literature. Studies suggest it may slow the rate of telomere shortening in aged cell models, a key marker in biological ageing research.

Pineal Gland and Melatonin Research
A significant body of research has explored Epitalon's interaction with the pineal gland and its role in melatonin synthesis regulation. Studies have found it may restore age-related decline in melatonin production, making it a key compound in circadian rhythm, sleep architecture, and neuroendocrine ageing research.

Neuroendocrine Regulation
Epitalon has been studied for its ability to normalise hypothalamic sensitivity and restore age-related dysregulation of the hypothalamic-pituitary axis. Research has explored its role in gonadotropin regulation, cortisol modulation, and broader neuroendocrine homeostasis in aged models.

Antioxidant and Cellular Protection Research
Studies have explored Epitalon's antioxidant properties, including its role in reducing lipid peroxidation, modulating superoxide dismutase activity, and protecting cellular structures from oxidative damage — making it a significant compound in oxidative stress and cellular longevity research.

Oncostatic Research
Epitalon has been studied in oncology research models for its potential role in inhibiting spontaneous tumour development and regulating oncogene expression in aged animal models. This represents one of the most active areas of Epitalon research in gerontological literature.

Each vial contains 10mg of lyophilized Epitalon with ≥99% purity, verified by third-party HPLC testing.

Intended strictly for research and laboratory use only. Not for human consumption.